Systematic Review: Effectiveness of Probiotic Giving as Additional Therapy in Atopic Dermatitis Patient
DOI:
https://doi.org/10.71341/bmwj.v1i2.21Keywords:
probiotics, atopic dermatitis, eczema, Th2 cells, inflammationAbstract
Background: Atopic dermatitis (AD), also known as eczema, is a chronic inflammatory skin condition affecting the epidermis and dermis. It is triggered by a combination of environmental and genetic factors, leading to symptoms such as polymorphic rashes and intense itching.
Objective: This systematic review aims to evaluate the effectiveness of oral probiotic supplementation as an adjunct therapy for individuals with atopic dermatitis.
Methods: The literature was reviewed by searching two electronic databases, Google Scholar and PubMed, resulting in the inclusion of eight studies that collectively involved 347 AD patients.
Results: The findings indicate that probiotic supplementation can significantly reduce the severity and incidence of atopic dermatitis. This effect is attributed to the inhibition of Th2 cell activity and a reduction in pro-inflammatory cytokines, including TNF-α and IgE, which are known contributors to the pathophysiology of AD.
Conclusion: Probiotics present a promising alternative for the prevention and management of atopic dermatitis, potentially enhancing patient outcomes.
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